PhytoCellTec™ Alp Rose

PhytoCellTec™ Alp Rose is a cosmetic active ingredient from the stem cells of the alpine rose.

The Alpine rose

The Alpine rose is a typical Swiss flower from the Alpine region. With its colorful pink flowers, it decorates mountain slopes at heights of up to 3200 m. Their evergreen leaves are extremely resistant to the strong UV radiation and the extraordinary cold. Even when the snow melts in the spring, the leaves shine bright and green. Responsible for this phenomenon is a protein, which the plant has more than abundantly: the dehydrin

Plant stem cells for skin stem cells

The researchers at Mibelle Biochemistry have researched the contents of the alpine rose for several years with its special protective substances and, above all, the water-storing dehydrin. With the help of the innovative technology PhytoCellTec ™ a formulation could be developed from the stem cells of the leaves which relieves dry and stressed skin and protects the skin stem cells demonstrably: PhytoCellTec ™ Alp Rose.

The effect

In comprehensive studies, Mibelle Biochemistry has shown that PhytoCellTec ™ Alp Rose promotes the vitality and life of the skin stem cells. The skin barrier is strengthened and the skin is better protected against climatic stress.


The effect of PhytoCellTec ™ Alp Rose combines two important approaches: The use of plant stem cells can delay skin ageing by protecting the vital skin stem cells. As a result, the skin remains young for a longer time and looks better and more vibrant. At the same time, PhytoCellTec ™ Alp Rose protects the skin with the special protection of this extremely resistant mountain plant.

Protection of epidermal stem cells against UV stress

Cell cultures with epidermal stem cells were treated with PhytoCellTec ™ Alp Rose, others remained untreated. Thereafter, the cells were all exposed to UVA and UVB rays. After the experiment, the ability to divide (Colony-Forming Efficiency, CFE) of the stem cells was determined. The results showed that UV radiation severely affects the ability to divide the cells. Through the treatment with PhytoCellTec ™ Alp Rose, the division capacity (vitality) of the stem cells increased and also protected the stem cells against UV radiation (see graphic).

Ski holiday study

In order to test the effect of PhytoCellTec ™ Alp Rose under extreme environmental conditions, 22 volunteers were treated with a sun protection formulation with protection factor 30 during their ski runs (March, Alps). One facial half was treated with the sun cream without active ingredient, on the other side the formulation contained the active ingredient PhytoCellTec ™ Alp Rose. After a further treatment week at home the skin moisture loss of the facial skin was measured. The results showed that the water loss could be reduced by 39% after 2 weeks. This is an indication that PhytoCellTec ™ Alp Rose strengthens the skin barrier and is more resistant to environmental stress such as UV, wind, cold and dryness (see graphic).

Protection of the epidermal
stem cells against UV stress

The division capacity of the stem cells can be obtained with
PhytoCellTec™ Alp Rose even after UV irradiation.

Ski holiday study
The effect of PhytoCellTec™ Alp Rose under extreme environmental conditions during 2 weeks. Result: 39% water loss could be prevented.

Ski holidays study
Visible skin wrinkle and rednesses / irritations could be reduced by 45% and 54% respectively.